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litothela
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 +1Posted on May 20th, 2013 | re: Monsters' Ball: The Week's Best Comments (46 comments)

You definitely make some great points, but we HAVE TO distinguish the issues of general breast cancer, and breast cancer risk due to hereditary breast and ovarian cancer (HBOC).

Changing your lifestyle and environmental factors that contribute to breast cancer and cancer in general is great. There are tons of studies currently underway looking at specific lifestyle factors for BRCA1/2 mutation carriers that can help them ameliorate their risk of breast, ovarian, and other cancers. Lifestyle change alone for BRCA1/2 carriers, however, WILL NOT reduce their risk of breast and ovarian cancer anywhere CLOSE to that of preventive surgeries. Genetics IS absolutely the main risk factor for this subgroup of people. You cannot eliminate the fact that the gene is mutated in every cell of their body.

People should have access to this genetic test, and should be able to choose whether to pursue these LITERALLY life-saving surgeries. If and only if there is a REASON to do it. For BRCA1/2 carriers, there is a reason. It really does suck that there is not a better risk-reducing option for BRCA1/2 carriers at this point. For the average person with breast cancer or a mild-moderate family history of breast cancer (not due to HBOC), there is not typically a reason to do these surgeries, and any competent genetic counselor/oncologist would not offer/recommend this.

 0Posted on May 20th, 2013 | re: Angelina Jolie's Double Mastectomy (37 comments)

litothela | Posted at 3:29pm 0

Her course of action is ASBOLUTELY a ‘recommended’/encouraged/offered option for women who carry BRCA1/2 mutations. It is NOT an irresponsible course of action. Please educate yourself about hereditary breast and ovarian cancer (again, a subset that accounts for only 5-10% of all cases of breast cancer) and the guidelines for screening/treatment/prevention. She is NOT advocating that the average woman, or even MOST women with a family history of breast cancer pursue these treatments.

You are VERY right that preventive mastectomies are NOT recommended for the average individual. But a person who carries a BRCA1/2 mutation is not the average individual.

- Your friendly neighbourhood videogummer who works in medical genetics and has seen dozens and dozens of patients with hereditary breast and ovarian cancer/other cancer predisposition syndromes

 0Posted on May 20th, 2013 | re: Angelina Jolie's Double Mastectomy (37 comments)

Her course of action is ASBOLUTELY a ‘recommended’/encouraged/offered option for women who carry BRCA1/2 mutations. It is NOT an irresponsible course of action. Please educate yourself about hereditary breast and ovarian cancer (again, a subset that accounts for only 5-10% of all cases of breast cancer) and the guidelines for screening/treatment/prevention. She is NOT advocating that the average woman, or even MOST women with a family history of breast cancer pursue these treatments.

You are VERY right that preventive mastectomies are NOT recommended for the average individual. But a person who carries a BRCA1/2 mutation is not the average individual.

- Your friendly neighbourhood videogummer who works in medical genetics and has seen dozens and dozens of patients with hereditary breast and ovarian cancer/other cancer predisposition syndromes

 +7Posted on Sep 29th, 2012 | re: Thursday Night TV Open Thread (47 comments)

“No offense, I just think Kelly is awful and an infant and has no idea what she’s talking about when it comes to anything. But totally no offense!!”
- you

 +2Posted on Sep 12th, 2012 | re: Reader Poll: Do You Agree With Nick Cassavetes About Incest? N/N? (68 comments)

1. Not true, my friend. Every couple in the general population has about a 2-3% chance to have a baby born with some sort of birth defect – this number encompasses things ranging from heart defects to cleft lips to recessive genetic conditions to Down syndrome. For first cousins, this risk doubles to be 4-6% chance of having a child with some sort of birth defect. (However, still means ~95% chance their babies will be fine!!) First generation breeding does have a higher chance of having a child with a genetic condition or birth defect. As relations get more distant from one and other, risks go down to get closer to the general population risk.

(I work in clinical genetics and occasionally see couples who are related to each other).

But yes, we totally have condoms and the pill =)! (..that wasn’t a sarcastic smiley).

 +7Posted on Jul 11th, 2012 | re: Daniel Tosh Encourages Audience To Rape Another Member Of Audience, LOL.0 (281 comments)

My brain just actually exploded due to the inanity of everything you just said. I am dead now and thankfully no longer on this planet.

 +3Posted on Jul 11th, 2012 | re: Daniel Tosh Encourages Audience To Rape Another Member Of Audience, LOL.0 (281 comments)

‘the line is funny’
Yeah I’m pretty positive it means something’s wrong with your brain.

 +3Posted on Jul 10th, 2012 | re: Daniel Tosh Encourages Audience To Rape Another Member Of Audience, LOL.0 (281 comments)

In a lovely, ideal world, when people said or did anything, you would be able to divine their true intent – everyone around them would understand what they really meant, who they are as a person, and what messages they actually want to send out to the world.

We do not live in this world, and when people in the media, with a large audience like this idiot has, say things like this, even if deep down he is a feminist (HA), the message is – I mean this thing, and it is okay for others to mean this thing also.

 +11Posted on Jul 10th, 2012 | re: Daniel Tosh Encourages Audience To Rape Another Member Of Audience, LOL.0 (281 comments)

Wait, in your head, a variation of ‘she should be gang-raped’ occurred, BEFORE you read what he said?

That was your first instinct? PLEASE EXAMINE YOUR LIFE IN THE MIRROR TONIGHT AND THINK ABOUT WHAT IS WRONG WITH YOUR BRAIN. Please.

 +3Posted on Jul 10th, 2012 | re: Daniel Tosh Encourages Audience To Rape Another Member Of Audience, LOL.0 (281 comments)

Nothing makes me HAPPIER than talk of gang-rape! What a blessed SOUL he is for trying to so kindly impart such joy and laughter upon the world.
(@jwormyk)

 +17Posted on May 29th, 2012 | re: It's Public Marriage Proposal Season Again (33 comments)

Whoa whoa, let’s all just look at the pure JOY and HAPPINESS on that woman’s face! It is her friends and family and loved ones, all in one place, complete with jokes about Dancing Jews and a proposal from a dude who clearly loves her a bunch. Look how happy they all are! Let’s be happy for them being happy?
I may have cried at this video. Please don’t mock me.

 +28Posted on Aug 22nd, 2011 | re: Duh Aficionado Magazine: January Jones Is One Of The Worst People On Earth (81 comments)

Whaaaaat?! What human being has a waist like this?! Inhuman photoshoppingargghrgg.

“when I sing live it is just the sound of a wild animal crashing through a haunted forest, shrieking as the demons continue their pursuit.”

I am going to LOL all evening at this.